Put the endorphins back

There's a point at which all rational avenues have been explored and exhausted. And yet, we're (and by we I mean anyone) still miserable. And I'm not talking "I feel cranky" miserable. I'm talking "I'll never feel good again" miserable. This is lack of seratonin. It's made easier to spot in some people by a craving for chocolate, but not everyone develops this symptom. When this point is reached, there's only one thing to do in order to get back to sanity. Boost the endorphin levels as quickly as possible. While oxcytocin is not seratonin, it's still a good start. Rationality is likely to follow.

Existential Curiosity

http://hasthelargehadroncolliderdestroyedtheworldyet.com/

On the Large Hadron Collider and Slaughterhouse 5

Tralfamadorian speaker: We know how the world ends and it has nothing to do with Earth, except that it gets wiped out too.
Billy Pilgrim: Really? How does it end?
Tralfamadorian speaker: While we're experimenting with new fuels, a Tralfamadorian test pilot panics, presses the wrong button, and the whole universe disappears.
Billy Pilgrim: But you have to stop him. If you know this, can't you keep the pilot from pressing ...
Tralfamadorian speaker: He has always pressed it, and he always will. We have always let him, and we always will let him. The moment is structured that way.